HOW HAZARDOUS MATERIALS EVADE THE LUNG’S DEFENCES BASIC INFORMATION


The airways of the respiratory system have developed an elaborate system of defences which trap all but the smallest dust particles. This system consists of hairs in the nose and mucus in the trachea or bronchi.

The mucus is produced continuously by special cells in the walls of the larger airways. It is moved upward and to the back of the throat by the whipping action of cilia—tiny, hair-like projections on the cells of the trachea and bronchi.

Large dust particles are trapped in the mucus and are either swallowed or spit out. Particles smaller than 0.5 microns (1 inch has 25,400 microns) may remain airborne and are exhaled.

The most dangerous size of dust particles is 0.5-7.0 microns. Much too small to be seen with the naked eye, they can evade the defence system and reach the lungs.

Once in the lungs, these tiny particles of dust may cause extensive scarring of the delicate air sacs. This scarring starts the disease process which produces severe shortness of breath.

Most dust particles are too large to pass through the walls of the alveoli, but gases, vapours, mists, and fumes can all enter the bloodstream through the lungs. In addition, welding fumes or truck exhausts can stimulate the lung’s defences to produce large amounts of phlegm, causing the condition known as chronic bronchitis.

These same substances can destroy the delicate air sacs of the lungs, causing emphysema.

Because the lungs are in such intimate contact with so many pollutants in workplace air, they are the prime target for occupational carcinogens.

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